Zika virus-specific therapy protects the fetal mouse brain

A gene-silencing therapy protected against Zika virus transmission from pregnant mice to the mouse fetuses, finds a new study. The treatment, which harnesses nanoparticles called small extracellular vesicles (sEVs) for drug delivery, crossed the placenta and blood-brain barrier to greatly reduce fetal neurological damage, including virus-induced brain shrinkage.

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